NIH – Phenotypic and Functional Characterization of ApoE2 to Inform Translation Strategies for Aging-Related Conditions
15/01/2018 09:50
Objetivo: To conduct basic and translational studies on ApoE2 and other variants to improve understanding of physiologic and cellular differences attributable to the ApoE e2 allele (vs. other ApoE alleles), and how they mediate ApoE e2’s differential effects on longevity and risk for age-related conditions. This will aid in the identification of potential therapeutic targets for interventions that prevent or ameliorate aging-related diseases by mimicking favorable differential effects of the ApoE e2 variant, while avoiding adverse effects.
Inscrições: até 16 de fevereiro de 2018
